Healthcare San Diego, CA Pop. 1,386,932

Medical Assistant Salary in San Diego, California

The median medical assistant salary in San Diego, CA is $57,405 per year, which is 50.0% above the national median and 2.7% above the California state average.

City Median
$57,405
vs State Avg
+$1,531
vs National
+$19,135
Cost of Living
142%

Medical Assistant Pay in San Diego: What to Expect (2026)

San Diego offers a median medical assistant salary of $57,405, which is $1,531 above the California state average of $55,874. Compared to the national median of $38,270, San Diego pays above average for this role.

However, San Diego's cost of living index is 142%, significantly above the national average. After adjusting for local costs, the $57,405 salary has an effective purchasing power of approximately $40,426. Housing, transportation, and food costs in San Diego should be factored into any relocation or job-change decision.

The salary range for medical assistants in San Diego spans from $44,100 at the 10th percentile to $78,000 at the 90th percentile — a $33,900 spread. Entry-level professionals start around $45,000, while senior medical assistants with 8+ years of experience can earn up to $72,000. As a major metro area with a population of 1,386,932, San Diego typically offers more job opportunities and employer competition, which can drive salaries higher.

Medical Assistant Salary in San Diego by Experience

In San Diego, an entry-level medical assistant earns around $45,000, while experienced professionals earn up to $72,000 per year. The local cost of living index is 142% of the national average.

Entry Level (0-2 yrs)
$45,000
+$15,000 vs national
Mid Level (3-7 yrs)
$57,000
+$19,000 vs national
Senior Level (8+ yrs)
$72,000
+$24,000 vs national

Salary Percentiles in San Diego, CA

Percentile San Diego
10th Percentile $44,100
25th Percentile $49,800
Median (50th) $57,405
75th Percentile $67,200
90th Percentile $78,000

Medical Assistant Salary in Other California Cities

How to Become a Medical Assistant in San Diego

Education

Most medical assistant positions require a postsecondary nondegree award. San Diego and the surrounding California area have institutions offering relevant programs.

Key Skills

Vital SignsPatient PrepMedical TerminologyEMR SystemsPhlebotomyScheduling

Job Outlook

Nationally, medical assistant employment is projected to grow 14% over the next decade (much faster than average). Demand in San Diego may vary based on local industry and population growth.

Find Medical Assistant Jobs in San Diego

Browse open medical assistant positions in San Diego, CA:

Frequently Asked Questions: Medical Assistant Salary in San Diego

How much does a Medical Assistant make in San Diego, CA? ▼
The median medical assistant salary in San Diego, California is $57,405 per year, which is 50.0% above the national median of $38,270. Salaries range from $44,100 (10th percentile) to $78,000 (90th percentile).
How much does a Medical Assistant make per hour in San Diego? ▼
Based on the median annual salary of $57,405, a medical assistant in San Diego earns approximately $28 per hour assuming a standard 2,080-hour work year.
How does San Diego compare to the California state average for medical assistant pay? ▼
San Diego's median medical assistant salary of $57,405 is 2.7% above the California state average of $55,874. The local cost of living index is 142% of the national average.
What is the cost of living in San Diego, CA? ▼
San Diego has a cost of living index of 142% compared to the national average. This means a medical assistant salary of $57,405 in San Diego has less purchasing power than the same salary in an average-cost city.
What qualifications do I need to become a medical assistant in San Diego? ▼
Most medical assistant positions in San Diego require a postsecondary nondegree award. Key skills include Vital Signs, Patient Prep, Medical Terminology, EMR Systems. The job market is projected to grow 14% nationally over the next decade.