Nurse Practitioner Salary in Winston-Salem, NC: $104,585 (2026)

Nurse Practitioner Pay in Winston-Salem: What to Expect (2026)

Winston-Salem offers a median nurse practitioner salary of $104,585, which is $7,296 below the North Carolina state average of $111,881. Compared to the national median of $121,610, Winston-Salem pays below the national benchmark for this role.

One of Winston-Salem's biggest advantages is its low cost of living at 86% of the national average. This means the $104,585 salary stretches further here — equivalent to roughly $121,610 in an average-cost city. This makes Winston-Salem an attractive option for nurse practitioners seeking strong real-dollar compensation.

The salary range for nurse practitioners in Winston-Salem spans from $74,906 at the 10th percentile to $144,652 at the 90th percentile — a $69,746 spread. Entry-level professionals start around $77,400, while senior nurse practitioners with 8+ years of experience can earn up to $133,300. With a population of 249,545, Winston-Salem is a mid-sized metro with a growing job market.

Nurse Practitioner Salary in Winston-Salem by Experience

In Winston-Salem, an entry-level nurse practitioner earns around $77,400, while experienced professionals earn up to $133,300 per year. The local cost of living index is 86% of the national average.

Entry Level (0-2 yrs)

$77,400

$-12,600 vs national

Mid Level (3-7 yrs)

$104,920

$-17,080 vs national

Senior Level (8+ yrs)

$133,300

$-21,700 vs national

Percentile	Winston-Salem	NC State	National
10th Percentile	$74,906	$80,132	$87,100
25th Percentile	$89,612	$95,864	$104,200
Median (50th)	$104,585	$111,881	$121,610
75th Percentile	$123,410	$132,020	$143,500
90th Percentile	$144,652	$154,744	$168,200

Percentile

Winston-Salem

10th Percentile

$74,906

25th Percentile

$89,612

Median (50th)

$104,585

75th Percentile

$123,410

90th Percentile

$144,652

How to Become a Nurse Practitioner in Winston-Salem

Education

Most nurse practitioner positions require a master's degree. Winston-Salem and the surrounding North Carolina area have institutions offering relevant programs.

Key Skills

Advanced AssessmentPharmacologyDiagnosisPatient EducationEMR SystemsClinical Decision-Making

Job Outlook

Nationally, nurse practitioner employment is projected to grow 40% over the next decade (much faster than average). Demand in Winston-Salem may vary based on local industry and population growth.

Frequently Asked Questions: Nurse Practitioner Salary in Winston-Salem

How much does a Nurse Practitioner make in Winston-Salem, NC? ▼

The median nurse practitioner salary in Winston-Salem, North Carolina is $104,585 per year, which is 14% below the national median of $121,610. Salaries range from $74,906 (10th percentile) to $144,652 (90th percentile).

How much does a Nurse Practitioner make per hour in Winston-Salem? ▼

Based on the median annual salary of $104,585, a nurse practitioner in Winston-Salem earns approximately $50 per hour assuming a standard 2,080-hour work year.

How does Winston-Salem compare to the North Carolina state average for nurse practitioner pay? ▼

Winston-Salem's median nurse practitioner salary of $104,585 is 6.5% below the North Carolina state average of $111,881. The local cost of living index is 86% of the national average.

What is the cost of living in Winston-Salem, NC? ▼

Winston-Salem has a cost of living index of 86% compared to the national average. This means a nurse practitioner salary of $104,585 in Winston-Salem has more purchasing power than the same salary in an average-cost city.

What qualifications do I need to become a nurse practitioner in Winston-Salem? ▼

Most nurse practitioner positions in Winston-Salem require a master's degree. Key skills include Advanced Assessment, Pharmacology, Diagnosis, Patient Education. The job market is projected to grow 40% nationally over the next decade.

Nurse Practitioner Salary in Winston-Salem, North Carolina