Physician Assistant Salary in San Francisco, California
The median physician assistant salary in San Francisco, CA is $239,419 per year, which is 90.0% above the national median and 30.1% above the California state average.
Physician Assistant Pay in San Francisco: What to Expect (2026)
San Francisco offers a median physician assistant salary of $239,419, which is $55,444 above the California state average of $183,975. Compared to the national median of $126,010, San Francisco pays above average for this role.
However, San Francisco's cost of living index is 182%, significantly above the national average. After adjusting for local costs, the $239,419 salary has an effective purchasing power of approximately $131,549. Housing, transportation, and food costs in San Francisco should be factored into any relocation or job-change decision.
The salary range for physician assistants in San Francisco spans from $159,600 at the 10th percentile to $330,600 at the 90th percentile — a $171,000 spread. Entry-level professionals start around $167,200, while senior physician assistants with 8+ years of experience can earn up to $307,800. As a major metro area with a population of 873,965, San Francisco typically offers more job opportunities and employer competition, which can drive salaries higher.
Physician Assistant Salary in San Francisco by Experience
In San Francisco, an entry-level physician assistant earns around $167,200, while experienced professionals earn up to $307,800 per year. The local cost of living index is 182% of the national average.
Salary Percentiles in San Francisco, CA
| Percentile | San Francisco |
|---|---|
| 10th Percentile | $159,600 |
| 25th Percentile | $201,400 |
| Median (50th) | $239,419 |
| 75th Percentile | $286,900 |
| 90th Percentile | $330,600 |
Physician Assistant Salary in Other California Cities
How to Become a Physician Assistant in San Francisco
Education
Most physician assistant positions require a master's degree. San Francisco and the surrounding California area have institutions offering relevant programs.
Key Skills
Job Outlook
Nationally, physician assistant employment is projected to grow 28% over the next decade (much faster than average). Demand in San Francisco may vary based on local industry and population growth.
Find Physician Assistant Jobs in San Francisco
Browse open physician assistant positions in San Francisco, CA: