Medical Assistant Salary in Missouri
The median medical assistant salary in Missouri is $33,678 per year, which is 12% below the national median of $38,270.
Medical Assistant Salary Overview in Missouri (2026)
Missouri ranks #42 out of 50 states for medical assistant compensation. Medical Assistant salaries in Missouri are below the national median, though the lower cost of living can offset the difference. At $33,678 per year, medical assistants in Missouri earn $4,592 less than the national median of $38,270.
A key advantage of working in Missouri is its below-average cost of living (88% of the national index). This means the $33,678 salary has the purchasing power of roughly $38,270 in an average-cost area.
The salary spread in Missouri is significant: medical assistants at the 10th percentile earn $25,872, while those at the 90th percentile bring home $45,760 — a $19,888 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in Missouri for this role is Kansas City, where the median reaches $35,208.
Nationally, medical assistant employment is projected to grow 14% over the next decade (much faster than average). This strong growth suggests increasing demand and competitive salaries in Missouri and beyond.
Medical Assistant Salary in Missouri by Experience
In Missouri, an entry-level medical assistant earns around $26,400, while experienced professionals earn up to $42,240 per year. The cost of living index in Missouri is 88% of the national average.
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Check Your Rate — No Credit Impact →Salary Percentiles in Missouri
| Percentile | MO Salary |
|---|---|
| 10th Percentile | $25,872 |
| 25th Percentile | $29,216 |
| Median (50th) | $33,678 |
| 75th Percentile | $39,424 |
| 90th Percentile | $45,760 |
Medical Assistant Salary by City in Missouri
The largest employment areas for medical assistants in Missouri include Kansas City, Saint Louis, Springfield, and Columbia. Salaries vary by city based on local cost of living and demand.
How to Become a Medical Assistant in Missouri
Education
Most medical assistant positions require a postsecondary nondegree award. Missouri has several accredited institutions offering relevant programs.
Key Skills
Job Outlook in Missouri
Nationally, medical assistant employment is projected to grow 14% over the next decade (much faster than average). Missouri's demand may vary based on local industry trends.
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