Healthcare South Dakota (SD) Rank #43 of 50

Medical Assistant Salary in South Dakota

The median medical assistant salary in South Dakota is $33,678 per year, which is 12% below the national median of $38,270.

Median Salary
$33,678
vs National
$-4,592
State Rank
#43 of 50
Cost of Living
88%

Medical Assistant Salary Overview in South Dakota (2026)

South Dakota ranks #43 out of 50 states for medical assistant compensation. Medical Assistant salaries in South Dakota are below the national median, though the lower cost of living can offset the difference. At $33,678 per year, medical assistants in South Dakota earn $4,592 less than the national median of $38,270.

A key advantage of working in South Dakota is its below-average cost of living (88% of the national index). This means the $33,678 salary has the purchasing power of roughly $38,270 in an average-cost area.

The salary spread in South Dakota is significant: medical assistants at the 10th percentile earn $25,872, while those at the 90th percentile bring home $45,760 — a $19,888 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in South Dakota for this role is Sioux Falls, where the median reaches $35,208.

Nationally, medical assistant employment is projected to grow 14% over the next decade (much faster than average). This strong growth suggests increasing demand and competitive salaries in South Dakota and beyond.

Medical Assistant Salary in South Dakota by Experience

In South Dakota, an entry-level medical assistant earns around $26,400, while experienced professionals earn up to $42,240 per year. The cost of living index in South Dakota is 88% of the national average.

Entry Level (0-2 yrs)
$26,400
$-3,600 vs national
Mid Level (3-7 yrs)
$33,440
$-4,560 vs national
Senior Level (8+ yrs)
$42,240
$-5,760 vs national

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Salary Percentiles in South Dakota

Percentile SD Salary
10th Percentile $25,872
25th Percentile $29,216
Median (50th) $33,678
75th Percentile $39,424
90th Percentile $45,760

Medical Assistant Salary by City in South Dakota

The largest employment areas for medical assistants in South Dakota include Sioux Falls, Rapid City, Aberdeen, and Brookings. Salaries vary by city based on local cost of living and demand.

How to Become a Medical Assistant in South Dakota

Education

Most medical assistant positions require a postsecondary nondegree award. South Dakota has several accredited institutions offering relevant programs.

Key Skills

Vital SignsPatient PrepMedical TerminologyEMR SystemsPhlebotomyScheduling

Job Outlook in South Dakota

Nationally, medical assistant employment is projected to grow 14% over the next decade (much faster than average). South Dakota's demand may vary based on local industry trends.

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Frequently Asked Questions: Medical Assistant Salary in South Dakota

How much does a Medical Assistant make in South Dakota? ▼
The median medical assistant salary in South Dakota is $33,678 per year, which is 12% below the national median of $38,270. Salaries range from $25,872 (10th percentile) to $45,760 (90th percentile).
How much does a Medical Assistant make per hour in South Dakota? ▼
Based on the median annual salary of $33,678, a medical assistant in South Dakota earns approximately $16 per hour assuming a standard 2,080-hour work year.
Is South Dakota a good state for medical assistants? ▼
South Dakota ranks #43 out of 50 states for medical assistant pay. The cost of living index is 88% of the national average. Entry-level medical assistants earn $26,400, while senior professionals earn $42,240.
How does South Dakota compare to other states for medical assistant salary? ▼
The highest paying state for medical assistants is Hawaii at $68,121. South Dakota's median of $33,678 ranks #43 nationally. Nearby-ranked states include South Carolina ($34,060) and Missouri ($33,678).
What is the entry-level medical assistant salary in South Dakota? ▼
An entry-level medical assistant in South Dakota earns approximately $26,400 per year. With 3-7 years of experience, pay increases to around $33,440. Senior-level professionals with 8+ years earn up to $42,240.
What city in South Dakota pays medical assistants the most? ▼
Sioux Falls is the highest paying city in South Dakota for medical assistants, with a median salary of $35,208. Other cities include Rapid City and Aberdeen.