Medical Assistant Salary in South Carolina
The median medical assistant salary in South Carolina is $34,060 per year, which is 11% below the national median of $38,270.
Medical Assistant Salary Overview in South Carolina (2026)
South Carolina ranks #41 out of 50 states for medical assistant compensation. Medical Assistant salaries in South Carolina are below the national median, though the lower cost of living can offset the difference. At $34,060 per year, medical assistants in South Carolina earn $4,210 less than the national median of $38,270.
A key advantage of working in South Carolina is its below-average cost of living (89% of the national index). This means the $34,060 salary has the purchasing power of roughly $38,270 in an average-cost area.
The salary spread in South Carolina is significant: medical assistants at the 10th percentile earn $26,166, while those at the 90th percentile bring home $46,280 — a $20,114 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in South Carolina for this role is Mount Pleasant, where the median reaches $40,184.
Nationally, medical assistant employment is projected to grow 14% over the next decade (much faster than average). This strong growth suggests increasing demand and competitive salaries in South Carolina and beyond.
Medical Assistant Salary in South Carolina by Experience
In South Carolina, an entry-level medical assistant earns around $26,700, while experienced professionals earn up to $42,720 per year. The cost of living index in South Carolina is 89% of the national average.
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Earning $34,060? You may qualify for student loan refinancing rates as low as 4.49% — potentially saving $14,000+ over the life of your loan.
Check Your Rate — No Credit Impact →Salary Percentiles in South Carolina
| Percentile | SC Salary |
|---|---|
| 10th Percentile | $26,166 |
| 25th Percentile | $29,548 |
| Median (50th) | $34,060 |
| 75th Percentile | $39,872 |
| 90th Percentile | $46,280 |
Medical Assistant Salary by City in South Carolina
The largest employment areas for medical assistants in South Carolina include Charleston, Columbia, Greenville, and North Charleston. Salaries vary by city based on local cost of living and demand.
How to Become a Medical Assistant in South Carolina
Education
Most medical assistant positions require a postsecondary nondegree award. South Carolina has several accredited institutions offering relevant programs.
Key Skills
Job Outlook in South Carolina
Nationally, medical assistant employment is projected to grow 14% over the next decade (much faster than average). South Carolina's demand may vary based on local industry trends.
Stand Out from the Competition
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