Healthcare Mississippi (MS) Rank #50 of 50

Physician Assistant Salary in Mississippi

The median physician assistant salary in Mississippi is $102,068 per year, which is 19% below the national median of $126,010.

Median Salary
$102,068
vs National
$-23,942
State Rank
#50 of 50
Cost of Living
83%

Physician Assistant Salary Overview in Mississippi (2026)

Mississippi ranks #50 out of 50 states for physician assistant compensation. Physician Assistant salaries in Mississippi are below the national median, though the lower cost of living can offset the difference. At $102,068 per year, physician assistants in Mississippi earn $23,942 less than the national median of $126,010.

A key advantage of working in Mississippi is its below-average cost of living (83% of the national index). This means the $102,068 salary has the purchasing power of roughly $122,973 in an average-cost area.

The salary spread in Mississippi is significant: physician assistants at the 10th percentile earn $68,040, while those at the 90th percentile bring home $140,940 — a $72,900 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in Mississippi for this role is Jackson, where the median reaches $104,588.

Nationally, physician assistant employment is projected to grow 28% over the next decade (much faster than average). This strong growth suggests increasing demand and competitive salaries in Mississippi and beyond.

Physician Assistant Salary in Mississippi by Experience

In Mississippi, an entry-level physician assistant earns around $71,280, while experienced professionals earn up to $131,220 per year. The cost of living index in Mississippi is 83% of the national average.

Entry Level (0-2 yrs)
$71,280
$-16,720 vs national
Mid Level (3-7 yrs)
$102,060
$-23,940 vs national
Senior Level (8+ yrs)
$131,220
$-30,780 vs national

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Salary Percentiles in Mississippi

Percentile MS Salary
10th Percentile $68,040
25th Percentile $85,860
Median (50th) $102,068
75th Percentile $122,310
90th Percentile $140,940

Physician Assistant Salary by City in Mississippi

The largest employment areas for physician assistants in Mississippi include Jackson, Gulfport, Southaven, and Hattiesburg. Salaries vary by city based on local cost of living and demand.

How to Become a Physician Assistant in Mississippi

Education

Most physician assistant positions require a master's degree. Mississippi has several accredited institutions offering relevant programs.

Key Skills

Clinical AssessmentPharmacologySurgical AssistingPatient CommunicationEMR SystemsDiagnosis

Job Outlook in Mississippi

Nationally, physician assistant employment is projected to grow 28% over the next decade (much faster than average). Mississippi's demand may vary based on local industry trends.

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Frequently Asked Questions: Physician Assistant Salary in Mississippi

How much does a Physician Assistant make in Mississippi? ▼
The median physician assistant salary in Mississippi is $102,068 per year, which is 19% below the national median of $126,010. Salaries range from $68,040 (10th percentile) to $140,940 (90th percentile).
How much does a Physician Assistant make per hour in Mississippi? ▼
Based on the median annual salary of $102,068, a physician assistant in Mississippi earns approximately $49 per hour assuming a standard 2,080-hour work year.
Is Mississippi a good state for physician assistants? ▼
Mississippi ranks #50 out of 50 states for physician assistant pay. The cost of living index is 83% of the national average. Entry-level physician assistants earn $71,280, while senior professionals earn $131,220.
How does Mississippi compare to other states for physician assistant salary? ▼
The highest paying state for physician assistants is Hawaii at $224,298. Mississippi's median of $102,068 ranks #50 nationally. Nearby-ranked states include Arkansas ($103,328) and West Virginia ($103,328).
What is the entry-level physician assistant salary in Mississippi? ▼
An entry-level physician assistant in Mississippi earns approximately $71,280 per year. With 3-7 years of experience, pay increases to around $102,060. Senior-level professionals with 8+ years earn up to $131,220.
What city in Mississippi pays physician assistants the most? ▼
Jackson is the highest paying city in Mississippi for physician assistants, with a median salary of $104,588. Other cities include Gulfport and Southaven.