Registered Nurse Salary in Mississippi
The median registered nurse salary in Mississippi is $65,788 per year, which is 19% below the national median of $81,220.
Registered Nurse Salary Overview in Mississippi (2026)
Mississippi ranks #50 out of 50 states for registered nurse compensation. Registered Nurse salaries in Mississippi are below the national median, though the lower cost of living can offset the difference. At $65,788 per year, registered nurses in Mississippi earn $15,432 less than the national median of $81,220.
A key advantage of working in Mississippi is its below-average cost of living (83% of the national index). This means the $65,788 salary has the purchasing power of roughly $79,263 in an average-cost area.
The salary spread in Mississippi is significant: registered nurses at the 10th percentile earn $46,494, while those at the 90th percentile bring home $97,848 — a $51,354 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in Mississippi for this role is Jackson, where the median reaches $67,413.
Nationally, registered nurse employment is projected to grow 6% over the next decade (faster than average). This steady growth indicates stable demand for registered nurses across the country.
Registered Nurse Salary in Mississippi by Experience
In Mississippi, an entry-level registered nurse earns around $46,980, while experienced professionals earn up to $93,150 per year. The cost of living index in Mississippi is 83% of the national average.
Build Wealth on Your Income
With a $65,788 income, financial advisors recommend investing 15–20% annually. Start building a diversified portfolio with as little as $10.
See Investment Options →Salary Percentiles in Mississippi
| Percentile | MS Salary |
|---|---|
| 10th Percentile | $46,494 |
| 25th Percentile | $54,108 |
| Median (50th) | $65,788 |
| 75th Percentile | $81,891 |
| 90th Percentile | $97,848 |
Registered Nurse Salary by City in Mississippi
The largest employment areas for registered nurses in Mississippi include Jackson, Gulfport, Southaven, and Hattiesburg. Salaries vary by city based on local cost of living and demand.
How to Become a Registered Nurse in Mississippi
Education
Most registered nurse positions require a bachelor's degree. Mississippi has several accredited institutions offering relevant programs.
Key Skills
Job Outlook in Mississippi
Nationally, registered nurse employment is projected to grow 6% over the next decade (faster than average). Mississippi's demand may vary based on local industry trends.
Stand Out from the Competition
85% of recruiters say a professionally written resume increases interview rates by 40%. Stand out from 3,175,390 other Registered Nurses.
Get a Professional Resume →Open to Registered Nurse Roles in Mississippi?
Get matched with recruiters hiring registered nurses in Mississippi at competitive salaries.
Or browse positions directly: