Healthcare Mississippi (MS) Rank #50 of 50

Nurse Practitioner Salary in Mississippi

The median nurse practitioner salary in Mississippi is $98,504 per year, which is 19% below the national median of $121,610.

Median Salary
$98,504
vs National
$-23,106
State Rank
#50 of 50
Cost of Living
83%

Nurse Practitioner Salary Overview in Mississippi (2026)

Mississippi ranks #50 out of 50 states for nurse practitioner compensation. Nurse Practitioner salaries in Mississippi are below the national median, though the lower cost of living can offset the difference. At $98,504 per year, nurse practitioners in Mississippi earn $23,106 less than the national median of $121,610.

A key advantage of working in Mississippi is its below-average cost of living (83% of the national index). This means the $98,504 salary has the purchasing power of roughly $118,680 in an average-cost area.

The salary spread in Mississippi is significant: nurse practitioners at the 10th percentile earn $70,551, while those at the 90th percentile bring home $136,242 — a $65,691 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in Mississippi for this role is Jackson, where the median reaches $100,936.

Nationally, nurse practitioner employment is projected to grow 40% over the next decade (much faster than average). This strong growth suggests increasing demand and competitive salaries in Mississippi and beyond.

Nurse Practitioner Salary in Mississippi by Experience

In Mississippi, an entry-level nurse practitioner earns around $72,900, while experienced professionals earn up to $125,550 per year. The cost of living index in Mississippi is 83% of the national average.

Entry Level (0-2 yrs)
$72,900
$-17,100 vs national
Mid Level (3-7 yrs)
$98,820
$-23,180 vs national
Senior Level (8+ yrs)
$125,550
$-29,450 vs national

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Salary Percentiles in Mississippi

Percentile MS Salary
10th Percentile $70,551
25th Percentile $84,402
Median (50th) $98,504
75th Percentile $116,235
90th Percentile $136,242

Nurse Practitioner Salary by City in Mississippi

The largest employment areas for nurse practitioners in Mississippi include Jackson, Gulfport, Southaven, and Hattiesburg. Salaries vary by city based on local cost of living and demand.

How to Become a Nurse Practitioner in Mississippi

Education

Most nurse practitioner positions require a master's degree. Mississippi has several accredited institutions offering relevant programs.

Key Skills

Advanced AssessmentPharmacologyDiagnosisPatient EducationEMR SystemsClinical Decision-Making

Job Outlook in Mississippi

Nationally, nurse practitioner employment is projected to grow 40% over the next decade (much faster than average). Mississippi's demand may vary based on local industry trends.

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Frequently Asked Questions: Nurse Practitioner Salary in Mississippi

How much does a Nurse Practitioner make in Mississippi? ▼
The median nurse practitioner salary in Mississippi is $98,504 per year, which is 19% below the national median of $121,610. Salaries range from $70,551 (10th percentile) to $136,242 (90th percentile).
How much does a Nurse Practitioner make per hour in Mississippi? ▼
Based on the median annual salary of $98,504, a nurse practitioner in Mississippi earns approximately $47 per hour assuming a standard 2,080-hour work year.
Is Mississippi a good state for nurse practitioners? ▼
Mississippi ranks #50 out of 50 states for nurse practitioner pay. The cost of living index is 83% of the national average. Entry-level nurse practitioners earn $72,900, while senior professionals earn $125,550.
How does Mississippi compare to other states for nurse practitioner salary? ▼
The highest paying state for nurse practitioners is Hawaii at $216,466. Mississippi's median of $98,504 ranks #50 nationally. Nearby-ranked states include Arkansas ($99,720) and West Virginia ($99,720).
What is the entry-level nurse practitioner salary in Mississippi? ▼
An entry-level nurse practitioner in Mississippi earns approximately $72,900 per year. With 3-7 years of experience, pay increases to around $98,820. Senior-level professionals with 8+ years earn up to $125,550.
What city in Mississippi pays nurse practitioners the most? ▼
Jackson is the highest paying city in Mississippi for nurse practitioners, with a median salary of $100,936. Other cities include Gulfport and Southaven.