Physician Assistant Salary in Missouri
The median physician assistant salary in Missouri is $110,889 per year, which is 12% below the national median of $126,010.
Physician Assistant Salary Overview in Missouri (2026)
Missouri ranks #42 out of 50 states for physician assistant compensation. Physician Assistant salaries in Missouri are below the national median, though the lower cost of living can offset the difference. At $110,889 per year, physician assistants in Missouri earn $15,121 less than the national median of $126,010.
A key advantage of working in Missouri is its below-average cost of living (88% of the national index). This means the $110,889 salary has the purchasing power of roughly $126,010 in an average-cost area.
The salary spread in Missouri is significant: physician assistants at the 10th percentile earn $73,920, while those at the 90th percentile bring home $153,120 — a $79,200 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in Missouri for this role is Kansas City, where the median reaches $115,929.
Nationally, physician assistant employment is projected to grow 28% over the next decade (much faster than average). This strong growth suggests increasing demand and competitive salaries in Missouri and beyond.
Physician Assistant Salary in Missouri by Experience
In Missouri, an entry-level physician assistant earns around $77,440, while experienced professionals earn up to $142,560 per year. The cost of living index in Missouri is 88% of the national average.
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View Offers You Qualify For →Salary Percentiles in Missouri
| Percentile | MO Salary |
|---|---|
| 10th Percentile | $73,920 |
| 25th Percentile | $93,280 |
| Median (50th) | $110,889 |
| 75th Percentile | $132,880 |
| 90th Percentile | $153,120 |
Physician Assistant Salary by City in Missouri
The largest employment areas for physician assistants in Missouri include Kansas City, Saint Louis, Springfield, and Columbia. Salaries vary by city based on local cost of living and demand.
How to Become a Physician Assistant in Missouri
Education
Most physician assistant positions require a master's degree. Missouri has several accredited institutions offering relevant programs.
Key Skills
Job Outlook in Missouri
Nationally, physician assistant employment is projected to grow 28% over the next decade (much faster than average). Missouri's demand may vary based on local industry trends.
Negotiate Your Way to Senior Pay
Data shows Physician Assistants who negotiate earn 7–15% more. A single negotiation could add $31,671 over your career trajectory.
Get Negotiation Scripts — $197 →Open to Physician Assistant Roles in Missouri?
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