Healthcare South Dakota (SD) Rank #43 of 50

Registered Nurse Salary in South Dakota

The median registered nurse salary in South Dakota is $71,474 per year, which is 12% below the national median of $81,220.

Median Salary
$71,474
vs National
$-9,746
State Rank
#43 of 50
Cost of Living
88%

Registered Nurse Salary Overview in South Dakota (2026)

South Dakota ranks #43 out of 50 states for registered nurse compensation. Registered Nurse salaries in South Dakota are below the national median, though the lower cost of living can offset the difference. At $71,474 per year, registered nurses in South Dakota earn $9,746 less than the national median of $81,220.

A key advantage of working in South Dakota is its below-average cost of living (88% of the national index). This means the $71,474 salary has the purchasing power of roughly $81,220 in an average-cost area.

The salary spread in South Dakota is significant: registered nurses at the 10th percentile earn $50,512, while those at the 90th percentile bring home $106,304 — a $55,792 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in South Dakota for this role is Sioux Falls, where the median reaches $74,722.

Nationally, registered nurse employment is projected to grow 6% over the next decade (faster than average). This steady growth indicates stable demand for registered nurses across the country.

Registered Nurse Salary in South Dakota by Experience

In South Dakota, an entry-level registered nurse earns around $51,040, while experienced professionals earn up to $101,200 per year. The cost of living index in South Dakota is 88% of the national average.

Entry Level (0-2 yrs)
$51,040
$-6,960 vs national
Mid Level (3-7 yrs)
$72,160
$-9,840 vs national
Senior Level (8+ yrs)
$101,200
$-13,800 vs national

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Salary Percentiles in South Dakota

Percentile SD Salary
10th Percentile $50,512
25th Percentile $58,784
Median (50th) $71,474
75th Percentile $88,968
90th Percentile $106,304

Registered Nurse Salary by City in South Dakota

The largest employment areas for registered nurses in South Dakota include Sioux Falls, Rapid City, Aberdeen, and Brookings. Salaries vary by city based on local cost of living and demand.

How to Become a Registered Nurse in South Dakota

Education

Most registered nurse positions require a bachelor's degree. South Dakota has several accredited institutions offering relevant programs.

Key Skills

Patient AssessmentMedication AdministrationCritical ThinkingCommunicationEMR SystemsBLS/ACLS

Job Outlook in South Dakota

Nationally, registered nurse employment is projected to grow 6% over the next decade (faster than average). South Dakota's demand may vary based on local industry trends.

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Frequently Asked Questions: Registered Nurse Salary in South Dakota

How much does a Registered Nurse make in South Dakota? ▼
The median registered nurse salary in South Dakota is $71,474 per year, which is 12% below the national median of $81,220. Salaries range from $50,512 (10th percentile) to $106,304 (90th percentile).
How much does a Registered Nurse make per hour in South Dakota? ▼
Based on the median annual salary of $71,474, a registered nurse in South Dakota earns approximately $34 per hour assuming a standard 2,080-hour work year.
Is South Dakota a good state for registered nurses? ▼
South Dakota ranks #43 out of 50 states for registered nurse pay. The cost of living index is 88% of the national average. Entry-level registered nurses earn $51,040, while senior professionals earn $101,200.
How does South Dakota compare to other states for registered nurse salary? ▼
The highest paying state for registered nurses is Hawaii at $144,572. South Dakota's median of $71,474 ranks #43 nationally. Nearby-ranked states include South Carolina ($72,286) and Missouri ($71,474).
What is the entry-level registered nurse salary in South Dakota? ▼
An entry-level registered nurse in South Dakota earns approximately $51,040 per year. With 3-7 years of experience, pay increases to around $72,160. Senior-level professionals with 8+ years earn up to $101,200.
What city in South Dakota pays registered nurses the most? ▼
Sioux Falls is the highest paying city in South Dakota for registered nurses, with a median salary of $74,722. Other cities include Rapid City and Aberdeen.