Healthcare South Dakota (SD) Rank #43 of 50

Pharmacist Salary in South Dakota

The median pharmacist salary in South Dakota is $116,820 per year, which is 12% below the national median of $132,750.

Median Salary
$116,820
vs National
$-15,930
State Rank
#43 of 50
Cost of Living
88%

Pharmacist Salary Overview in South Dakota (2026)

South Dakota ranks #43 out of 50 states for pharmacist compensation. Pharmacist salaries in South Dakota are below the national median, though the lower cost of living can offset the difference. At $116,820 per year, pharmacists in South Dakota earn $15,930 less than the national median of $132,750.

A key advantage of working in South Dakota is its below-average cost of living (88% of the national index). This means the $116,820 salary has the purchasing power of roughly $132,750 in an average-cost area.

The salary spread in South Dakota is significant: pharmacists at the 10th percentile earn $84,656, while those at the 90th percentile bring home $145,904 — a $61,248 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in South Dakota for this role is Sioux Falls, where the median reaches $122,130.

Nationally, pharmacist employment is projected to grow 2% over the next decade (slower than average). This steady growth indicates stable demand for pharmacists across the country.

Pharmacist Salary in South Dakota by Experience

In South Dakota, an entry-level pharmacist earns around $88,000, while experienced professionals earn up to $139,040 per year. The cost of living index in South Dakota is 88% of the national average.

Entry Level (0-2 yrs)
$88,000
$-12,000 vs national
Mid Level (3-7 yrs)
$114,400
$-15,600 vs national
Senior Level (8+ yrs)
$139,040
$-18,960 vs national

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Salary Percentiles in South Dakota

Percentile SD Salary
10th Percentile $84,656
25th Percentile $102,960
Median (50th) $116,820
75th Percentile $133,936
90th Percentile $145,904

Pharmacist Salary by City in South Dakota

The largest employment areas for pharmacists in South Dakota include Sioux Falls, Rapid City, Aberdeen, and Brookings. Salaries vary by city based on local cost of living and demand.

How to Become a Pharmacist in South Dakota

Education

Most pharmacist positions require a doctoral degree. South Dakota has several accredited institutions offering relevant programs.

Key Skills

PharmacologyPatient CounselingDrug InteractionsCompoundingClinical ReviewPharmacy Software

Job Outlook in South Dakota

Nationally, pharmacist employment is projected to grow 2% over the next decade (slower than average). South Dakota's demand may vary based on local industry trends.

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Frequently Asked Questions: Pharmacist Salary in South Dakota

How much does a Pharmacist make in South Dakota? ▼
The median pharmacist salary in South Dakota is $116,820 per year, which is 12% below the national median of $132,750. Salaries range from $84,656 (10th percentile) to $145,904 (90th percentile).
How much does a Pharmacist make per hour in South Dakota? ▼
Based on the median annual salary of $116,820, a pharmacist in South Dakota earns approximately $56 per hour assuming a standard 2,080-hour work year.
Is South Dakota a good state for pharmacists? ▼
South Dakota ranks #43 out of 50 states for pharmacist pay. The cost of living index is 88% of the national average. Entry-level pharmacists earn $88,000, while senior professionals earn $139,040.
How does South Dakota compare to other states for pharmacist salary? ▼
The highest paying state for pharmacists is Hawaii at $236,295. South Dakota's median of $116,820 ranks #43 nationally. Nearby-ranked states include South Carolina ($118,148) and Missouri ($116,820).
What is the entry-level pharmacist salary in South Dakota? ▼
An entry-level pharmacist in South Dakota earns approximately $88,000 per year. With 3-7 years of experience, pay increases to around $114,400. Senior-level professionals with 8+ years earn up to $139,040.
What city in South Dakota pays pharmacists the most? ▼
Sioux Falls is the highest paying city in South Dakota for pharmacists, with a median salary of $122,130. Other cities include Rapid City and Aberdeen.