Healthcare South Dakota (SD) Rank #43 of 50

Nurse Practitioner Salary in South Dakota

The median nurse practitioner salary in South Dakota is $107,017 per year, which is 12% below the national median of $121,610.

Median Salary
$107,017
vs National
$-14,593
State Rank
#43 of 50
Cost of Living
88%

Nurse Practitioner Salary Overview in South Dakota (2026)

South Dakota ranks #43 out of 50 states for nurse practitioner compensation. Nurse Practitioner salaries in South Dakota are below the national median, though the lower cost of living can offset the difference. At $107,017 per year, nurse practitioners in South Dakota earn $14,593 less than the national median of $121,610.

A key advantage of working in South Dakota is its below-average cost of living (88% of the national index). This means the $107,017 salary has the purchasing power of roughly $121,610 in an average-cost area.

The salary spread in South Dakota is significant: nurse practitioners at the 10th percentile earn $76,648, while those at the 90th percentile bring home $148,016 — a $71,368 gap that reflects differences in experience, specialization, employer type, and metro area. The highest-paying city in South Dakota for this role is Sioux Falls, where the median reaches $111,881.

Nationally, nurse practitioner employment is projected to grow 40% over the next decade (much faster than average). This strong growth suggests increasing demand and competitive salaries in South Dakota and beyond.

Nurse Practitioner Salary in South Dakota by Experience

In South Dakota, an entry-level nurse practitioner earns around $79,200, while experienced professionals earn up to $136,400 per year. The cost of living index in South Dakota is 88% of the national average.

Entry Level (0-2 yrs)
$79,200
$-10,800 vs national
Mid Level (3-7 yrs)
$107,360
$-14,640 vs national
Senior Level (8+ yrs)
$136,400
$-18,600 vs national

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Salary Percentiles in South Dakota

Percentile SD Salary
10th Percentile $76,648
25th Percentile $91,696
Median (50th) $107,017
75th Percentile $126,280
90th Percentile $148,016

Nurse Practitioner Salary by City in South Dakota

The largest employment areas for nurse practitioners in South Dakota include Sioux Falls, Rapid City, Aberdeen, and Brookings. Salaries vary by city based on local cost of living and demand.

How to Become a Nurse Practitioner in South Dakota

Education

Most nurse practitioner positions require a master's degree. South Dakota has several accredited institutions offering relevant programs.

Key Skills

Advanced AssessmentPharmacologyDiagnosisPatient EducationEMR SystemsClinical Decision-Making

Job Outlook in South Dakota

Nationally, nurse practitioner employment is projected to grow 40% over the next decade (much faster than average). South Dakota's demand may vary based on local industry trends.

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Frequently Asked Questions: Nurse Practitioner Salary in South Dakota

How much does a Nurse Practitioner make in South Dakota? ▼
The median nurse practitioner salary in South Dakota is $107,017 per year, which is 12% below the national median of $121,610. Salaries range from $76,648 (10th percentile) to $148,016 (90th percentile).
How much does a Nurse Practitioner make per hour in South Dakota? ▼
Based on the median annual salary of $107,017, a nurse practitioner in South Dakota earns approximately $51 per hour assuming a standard 2,080-hour work year.
Is South Dakota a good state for nurse practitioners? ▼
South Dakota ranks #43 out of 50 states for nurse practitioner pay. The cost of living index is 88% of the national average. Entry-level nurse practitioners earn $79,200, while senior professionals earn $136,400.
How does South Dakota compare to other states for nurse practitioner salary? ▼
The highest paying state for nurse practitioners is Hawaii at $216,466. South Dakota's median of $107,017 ranks #43 nationally. Nearby-ranked states include South Carolina ($108,233) and Missouri ($107,017).
What is the entry-level nurse practitioner salary in South Dakota? ▼
An entry-level nurse practitioner in South Dakota earns approximately $79,200 per year. With 3-7 years of experience, pay increases to around $107,360. Senior-level professionals with 8+ years earn up to $136,400.
What city in South Dakota pays nurse practitioners the most? ▼
Sioux Falls is the highest paying city in South Dakota for nurse practitioners, with a median salary of $111,881. Other cities include Rapid City and Aberdeen.